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Article

HLA class II polymorphisms and recurrent spontaneous abortion in a Southern Brazilian cohort.

International journal of immunogenetics - 1 Jun 2013

Bompeixe E P, Carvalho Santos P S, Vargas R G, von Linsingen R, Zeck S C, Wowk P F, Bicalho M G

Abstract excerpt

A high proportion of human recurrent spontaneous abortions (RSA) remain unexplained. The possible association between RSA and different genetic polymorphisms within the human leucocyte antigen system (HLA system, the human major histocompatibility complex) has been investigated with conflicting results since many decades. Here, we describe a case-control study with 136 Southern Brazilian women of predominantly...

Topics

Abortion, Habitual
Adult
Brazil
Case-Control Studies
Cytokines
Female
Gene Frequency
Genotype
HLA-DQ beta-Chains
HLA-DRB1 Chains
Histocompatibility Antigens Class II

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Phenotype

Polymorphism, Genetic

Pregnancy

Source

Identifiers

PMID: 22938381
DOI: 10.1111/j.1744-313X.2012.01155.x

Genes

IFNG

Provenance

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