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Article

Genetic variation in the HSD3B1 gene and recurrent spontaneous abortions.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians - 1 Apr 2012

Ntostis Panagiotis, Peraki Ourania, Boulgari Alexandra, Agiannitopoulos Konstantinos, Pantos Konstantinos, Lamnissou Klea

Abstract excerpt

OBJECTIVE: HSD3B1 gene encodes the 3β-hydroxysteroid deydrogenases/isomerase (3β-HSD) enzyme, which plays a crucial role in the biosynthesis of all hormonal steroids. The aim of this study was to examine the potential impact of a T → C substitution at codon Leu(338) of HSD3B1 gene on pregnancy outcome. METHODS: In this prospective case-control study, 162 patients and 139 healthy controls were investigated for the...

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PMID: 21631238
DOI: 10.3109/14767058.2011.582199

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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