Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Contact-dependent growth inhibition toxins exploit multiple independent cell-entry pathways.

Proceedings of the National Academy of Sciences of the United States of America - 8 Sept 2015

Willett Julia L E, Gucinski Grant C, Fatherree Jackson P, Low David A, Hayes Christopher S

Abstract excerpt

Contact-dependent growth inhibition (CDI) systems function to deliver toxins into neighboring bacterial cells. CDI+ bacteria export filamentous CdiA effector proteins, which extend from the inhibitor-cell surface to interact with receptors on neighboring target bacteria. Upon binding its receptor, CdiA delivers a toxin derived from its C-terminal region. CdiA C-terminal (CdiA-CT) sequences are highly variable...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Adhesion
Share to Bacterial Toxins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Escherichia coli

Share to Escherichia coli Proteins

Share to Microscopy, Fluorescence

Share to Protein Transport

Share to Sequence Homology, Amino Acid

Share to Species Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 26305955
DOI: 10.1073/pnas.1512124112
PMCID: PMC4568652

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Contact-dependent growth inhibition toxins exploit multiple independent cell-entry pathways.PMID 26305955Read ↗

Functional and Structural Diversity of Bacterial Contact-Dependent Growth Inhibition EffectorsSemantic proximity Read ↗

CdiA from Enterobacter cloacae delivers a toxic ribosomal RNase into target bacteria.Semantic proximity Read ↗

Genetic Evidence for SecY Translocon-Mediated Import of Two Contact-Dependent Growth Inhibition (CDI) Toxins.Semantic proximity Read ↗

Genetic analysis of the CDI pathway from Burkholderia pseudomallei 1026b.Semantic proximity Read ↗

Contact-dependent inhibition of growth in Escherichia coli.Semantic proximity Read ↗

The C. difficile toxin B membrane translocation machinery is an evolutionarily conserved protein delivery apparatusSemantic proximity Read ↗

Interbacterial signaling via <i>Burkholderia</i> contact-dependent growth inhibition system proteinsSemantic proximity Read ↗

The Coxiella burnetii Dot/Icm system delivers a unique repertoire of type IV effectors into host cells and is required for intracellular replication.Semantic proximity Read ↗

The toxin/immunity network of <i>Burkholderia pseudomallei</i> contact‐dependent growth inhibition (CDI) systemsSemantic proximity Read ↗

CdiA promotes receptor-independent intercellular adhesion.Semantic proximity Read ↗

A new contact killing toxin permeabilizes cells and belongs to a large protein familySemantic proximity Read ↗

Molecular Basis for Immunity Protein Recognition of a Type VII Secretion System Exported Antibacterial Toxin.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.