Article
Molecular Basis for Immunity Protein Recognition of a Type VII Secretion System Exported Antibacterial Toxin.
Journal of molecular biology - 19 Oct 2018
Klein Timothy A, Pazos Manuel, Surette Michael G, Vollmer Waldemar, Whitney John C
Abstract excerpt
Gram-positive bacteria deploy the type VII secretion system (T7SS) to facilitate interactions between eukaryotic and prokaryotic cells. In recent work, we identified the TelC protein from Streptococcus intermedius as a T7SS-exported lipid II phosphatase that mediates interbacterial competition. TelC exerts toxicity in the inner wall zone of Gram-positive bacteria; however, intercellular intoxication of sister...
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