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Article

Genomic Copy Number Variations of the Complement Component C4B Gene Are Associated With Chronic Central Serous Chorioretinopathy.

Investigative ophthalmology & visual science - 1 Aug 2015

Breukink Myrte B, Schellevis Rosa L, Boon Camiel J F, Fauser Sascha, Hoyng Carel B, den Hollander Anneke I, de Jong Eiko K

Abstract excerpt

PURPOSE: Chronic central serous chorioretinopathy (cCSC) has recently been associated to variants in the complement factor H gene. To further investigate the role of the complement system in cCSC, the genomic copy number variations in the complement component 4 gene (C4) were studied. METHODS: C4A and C4B copy numbers were analyzed in 197 cCSC patients and 303 healthy controls by using a Taqman copy number...

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Identifiers

PMID: 26305533
DOI: 10.1167/iovs.15-17343

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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