Article
Common variants in the complement factor H gene confer genetic susceptibility to central serous chorioretinopathy.
Ophthalmology - 1 May 2014
Miki Akiko, Kondo Naoshi, Yanagisawa Suiho, Bessho Hiroaki, Honda Shigeru, Negi Akira
Abstract excerpt
PURPOSE: To investigate whether complement factor H (CFH) gene DNA variants are associated with central serous chorioretinopathy (CSCR). DESIGN: Cross-sectional study. PARTICIPANTS: A case-control group of 140 CSCR subjects and 2 different control groups: 934 population-based controls and 335 hospital-based controls. METHODS: Five single-nucleotide polymorphisms (SNPs) in CFH (rs3753394, rs800292, rs2284664,...
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