Article
Role of the Complement System in Chronic Central Serous Chorioretinopathy: A Genome-Wide Association Study.
JAMA ophthalmology - 1 Oct 2018
Schellevis Rosa L, van Dijk Elon H C, Breukink Myrte B, Altay Lebriz, Bakker Bjorn, Koeleman Bobby P C, Kiemeney Lambertus A, Swinkels Dorine W, Keunen Jan E E, Fauser Sascha, Hoyng Carel B, den Hollander Anneke I, Boon Camiel J F, de Jong Eiko K
Abstract excerpt
Importance: To date, several targeted genetic studies on chronic central serous chorioretinopathy (cCSC) have been performed; however, unbiased genome-wide studies into the genetics of cCSC have not been reported. To discover new genetic loci associated with cCSC and to better understand the causative mechanism of this disease, we performed a genome-wide association study (GWAS) on patients with cCSC. Objective:...
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