Article
Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.
Arthritis and rheumatism - 1 Nov 2013
Hou Shengping, Qi Jian, Liao Dan, Zhang Qi, Fang Jing, Zhou Yan, Liu Yunjia, Bai Lin, Zhang Meifen, Kijlstra Aize, Yang Peizeng
Abstract excerpt
OBJECTIVE: Complement component C4 copy number variations are associated with various inflammatory diseases. This study was undertaken to investigate whether copy number variations of C4 are also involved in the pathogenesis of Behçet's disease (BD). METHODS: Gene expression was examined by enzyme-linked immunosorbent assay (ELISA) or real-time polymerase chain reaction (PCR). Copy number variations of C4...
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