Article
Fibrinogen and α1-antitrypsin in COPD exacerbations.
Thorax - 1 Nov 2015
Ingebrigtsen Truls S, Marott Jacob L, Rode Line, Vestbo Jørgen, Lange Peter, Nordestgaard Børge G
Abstract excerpt
BACKGROUND: We tested the hypotheses that fibrinogen and α1-antitrypsin are observationally and genetically associated with exacerbations in COPD. METHODS: We studied 13,591 individuals with COPD from the Copenhagen General Population Study (2003-2013), of whom 6857 were genotyped for FGB -455 (rs1800790, G>A) and FGB -448 (rs4220, G>A) and had plasma fibrinogen measured. Furthermore, 13,405 individuals were...
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