Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphic variation in surfactant protein B is associated with COPD exacerbations.

The European respiratory journal - 1 Oct 2008

Foreman M G, DeMeo D L, Hersh C P, Carey V J, Fan V S, Reilly J J, Shapiro S D, Silverman E K

Abstract excerpt

Exacerbations of chronic obstructive pulmonary disease (COPD) reduce quality of life and increase mortality. Genetic variation might explain the substantial variability seen in exacerbation frequency among COPD subjects with similar lung function. Polymorphisms in five candidate genes, previously associated with COPD susceptibility, were analysed in order to determine whether they demonstrated association with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Alleles
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Genetic

Share to Pulmonary Disease, Chronic Obstructive

Share to Pulmonary Surfactant-Associated Protein B

Share to Regression Analysis

Share to Smoking

Source

Open in PubMed Open full text

Identifiers

PMID: 18550614
DOI: 10.1183/09031936.00040208
PMCID: PMC2761762

Genes

SFTPB
EPHX1
GSTP1
SERPINE2
TGFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphic variation in surfactant protein B is associated with COPD exacerbations.PMID 18550614Read ↗

Genetic associations with hypoxemia and pulmonary arterial pressure in COPD.Semantic proximity Read ↗

Association of surfactant protein B gene with chronic obstructive pulmonary disease susceptibility.Semantic proximity Read ↗

Genetic association analysis of COPD candidate genes with bronchodilator responsiveness.Semantic proximity Read ↗

Surfactant protein B polymorphisms, pulmonary function and COPD in 10,231 individuals.Semantic proximity Read ↗

Polymorphisms in surfactant protein-D are associated with chronic obstructive pulmonary disease.Semantic proximity Read ↗

Exacerbations in chronic obstructive pulmonary disease: do they contribute to disease progression?Semantic proximity Read ↗

Rare surfactant‐related variants in familial and sporadic pulmonary fibrosisSemantic proximity Read ↗

Genetic association analysis of functional impairment in chronic obstructive pulmonary disease.Semantic proximity Read ↗

Surfactant protein gene A, B, and D marker alleles in chronic obstructive pulmonary disease of a Mexican population.Semantic proximity Read ↗

Surfactant protein A and B genetic variants predispose to idiopathic pulmonary fibrosis.Semantic proximity Read ↗

Effect of ADRB2 polymorphisms on the efficacy of salmeterol and tiotropium in preventing COPD exacerbations: a prespecified substudy of the POET-COPD trial.Semantic proximity Read ↗

Functional polymorphisms in surfactant protein genes and chronic obstructive pulmonary disease risk: a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.