Article
Integration of microarray analysis into the clinical diagnosis of hematological malignancies: How much can we improve cytogenetic testing?
Oncotarget - 7 Aug 2015
Peterson Jess F, Aggarwal Nidhi, Smith Clayton A, Gollin Susanne M, Surti Urvashi, Rajkovic Aleksandar, Swerdlow Steven H, Yatsenko Svetlana A
Abstract excerpt
PURPOSE: To evaluate the clinical utility, diagnostic yield and rationale of integrating microarray analysis in the clinical diagnosis of hematological malignancies in comparison with classical chromosome karyotyping/fluorescence in situ hybridization (FISH). METHODS: G-banded chromosome analysis, FISH and microarray studies using customized CGH and CGH+SNP designs were performed on 27 samples from patients with...
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