Article
The Utilization of Chromosomal Microarray Technologies for Hematologic Neoplasms: An ACLPS Critical Review.
American journal of clinical pathology - 1 Oct 2018
Peterson Jess F, Van Dyke Daniel L, Hoppman Nicole L, Kearney Hutton M, Sukov William R, Greipp Patricia T, Ketterling Rhett P, Baughn Linda B
Abstract excerpt
OBJECTIVES: Chromosome (G-banding) and fluorescence in situ hybridization (FISH) serve as the primary methodologies utilized for detecting genetic aberrations in hematologic neoplasms. Chromosomal microarray can detect copy number aberrations (CNAs) with greater resolution when compared to G-banding and FISH, and can also identify copy-neutral loss of heterozygosity (CN-LOH). The purpose of our review is to...
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