Article
Genetic Variation on TNF/LTA and TNFRSF1A Genes is Associated with Outcomes of Hepatitis C Virus Infection.
Immunological investigations - 1 Jan 2021
Yue Ming, Huang Peng, Wang Chunhui, Fan Haozhi, Tian Ting, Wu Jingjing, Luo Fan, Fu Zuqiang, Xia Xueshan, Zhu Ping, Li Jun, Han Yaping, Zhang Yun, Hou Wei
Abstract excerpt
Hepatitis C virus (HCV) infections are a serious global-scaled public health problem. Tumor necrosis factor (TNF)/lymphotoxin alpha (LTA) has been found to play a crucial role in relation to the outcomes of HCV infection after it binds to TNF receptor superfamily member 1A (TNFRSF1A). Thus, we investigated whether or not the TNF/LTA gene cluster and TNFRSF1A gene polymorphisms were associated with the outcomes of...
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