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Article

Toll-like receptors in the pathogenesis of human B cell malignancies

11 Aug 2014

Abstract excerpt

Toll-like receptors (TLRs) are important players in B-cell activation, maturation and memory and may be involved in the pathogenesis of B-cell lymphomas. Accumulating studies show differential expression in this heterogeneous group of cancers. Stimulation with TLR specific ligands, or agonists of their ligands, leads to aberrant responses in the malignant B-cells. According to current data, TLRs can be implicated...

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PMID: 25112836
DOI: 10.1186/s13045-014-0057-5

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