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Article

Hepatitis C virus Genotype 1a core gene nucleotide patterns associated with hepatocellular carcinoma risk.

The Journal of general virology - 1 Sept 2015

Korba Brent, Shetty Kirti, Medvedev Alexei, Viswanathan Prasanth, Varghese Rency, Zhou Bin, Roy Rabindra, Makambi Kepher, Ressom Habtom, Loffredo Christopher A

Abstract excerpt

Specific sequence changes in codons 70 and 91 of the hepatitis C virus genotype 1b (HCV GT1b) core gene have been associated with increased risk of hepatocellular carcinoma (HCC). Essentially all previous studies were conducted in Asian populations with a wide range of liver disease, and none were conducted specifically in GT1a-infected individuals. We conducted a pilot study in a multiethnic population in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26296571
DOI: 10.1099/jgv.0.000219
PMCID: PMC4857454

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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