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Article

Functional equivalence of an evolutionarily conserved RNA binding module.

The Journal of biological chemistry - 2 Oct 2015

Wells Melissa L, Hicks Stephanie N, Perera Lalith, Blackshear Perry J

Abstract excerpt

Members of the tristetraprolin (TTP) family of proteins participate in the regulation of mRNA turnover after initially binding to AU-rich elements in target mRNAs. Related proteins from most groups of eukaryotes contain a conserved tandem zinc finger (TZF) domain consisting of two closely spaced, similar CCCH zinc fingers that form the primary RNA binding domain. There is considerable sequence variation within...

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Identifiers

PMID: 26292216
DOI: 10.1074/jbc.M115.673012
PMCID: PMC4591824

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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