Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential nuclear ATRX expression in sarcomas.

Histopathology - 1 Apr 2016

Koelsche Christian, Renner Marcus, Johann Pascal, Leiss Irina, Sahm Felix, Schimmack Simon, Wardelmann Eva, Renker Eva-Kristin, Schirmacher Peter, Korshunov Andrey, von Deimling Andreas, Mechtersheimer Gunhild

Abstract excerpt

AIM: Nuclear α-thalassemia/mental retardation X-linked (ATRX) loss and alternative lengthening of telomeres (ALT) are linked in distinct malignancies. We therefore aimed to determine the nuclear ATRX expression correlated with ALT in a comprehensive series of sarcomas. METHODS AND RESULTS: A total of 573 formalin-fixed paraffin-embedded sarcomas comprising 28 entities were investigated for nuclear ATRX expression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Substitution
Share to Codon, Nonsense

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to In Situ Hybridization, Fluorescence

Share to Phenotype

Share to Sarcoma

Share to Telomere

Share to Telomere Homeostasis

Share to X-linked Nuclear Protein

Source

Identifiers

PMID: 26291601
DOI: 10.1111/his.12812

Genes

ATRX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential nuclear ATRX expression in sarcomas.PMID 26291601Read ↗

Alternative lengthening of telomeres phenotype and loss of ATRX expression in sarcomas (Review)Semantic proximity Read ↗

Comprehensive screening of alternative lengthening of telomeres phenotype and loss of ATRX expression in sarcomas.Semantic proximity Read ↗

Loss of ATRX/DAXX expression and alternative lengthening of telomeres in uterine leiomyomasSemantic proximity Read ↗

Leiomyosarcoma With Alternative Lengthening of Telomeres Is Associated With Aggressive Histologic Features, Loss of ATRX Expression, and Poor Clinical OutcomeSemantic proximity Read ↗

ATRX Alteration Contributes to Tumor Growth and Immune Escape in Pleomorphic SarcomasSemantic proximity Read ↗

ATRX alteration contributes to tumor growth and immune escape in pleomorphic sarcomasSemantic proximity Read ↗

ATRX loss in sarcomas is associated with dysregulated gene and transposable element expression, loss of DNA methylation, and worse survivalSemantic proximity Read ↗

Alpha thalassemia/mental retardation X-linked (ATRX) protein expression in human pituitary neuroendocrine tumours and its reported correlation to prognosis and clinical outcomes: A systematic reviewSemantic proximity Read ↗

Exome Sequencing of Uterine Leiomyosarcomas Identifies Frequent Mutations in TP53, ATRX, and MED12Semantic proximity Read ↗

ATRX and Its Prognostic Significance in Soft Tissue SarcomaSemantic proximity Read ↗

Telomeres and telomerase in Sarcoma disease and therapy.Semantic proximity Read ↗

Alternative Lengthening of Telomeres in Malignant Perivascular Epithelioid Cell Neoplasms: Correlation With Molecular Features Including ATRX Gene Mutation Status.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.