Article
Telomeres and telomerase in Sarcoma disease and therapy.
International journal of medical sciences - 1 Jan 2024
Huang Jin, Feng Yan, Shi YangJing, Shao Weilin, Li Genshan, Chen Gangxian, Li Ying, Yang Zuozhang, Yao Zhihong
Abstract excerpt
Sarcoma is a rare tumor derived from the mesenchymal tissue and mainly found in children and adolescents. The outcome for patients with sarcoma is relatively poor compared with that for many other solid malignant tumors. Sarcomas have a highly heterogeneous pathogenesis, histopathology and biological behavior. Dysregulated signaling pathways and various gene mutations are frequently observed in sarcomas. The...
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