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Article

Comprehensive screening of alternative lengthening of telomeres phenotype and loss of ATRX expression in sarcomas.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Dec 2015

Liau Jau-Yu, Lee Jen-Chieh, Tsai Jia-Huei, Yang Ching-Yao, Liu Tsung-Lin, Ke Zhi-Long, Hsu Hung-Han, Jeng Yung-Ming

Abstract excerpt

According to cytogenetic aberrations, sarcomas can be categorized as complex or simple karyotype tumors. Alternative lengthening of telomeres is a telomere-maintenance mechanism common in sarcomas. Recently, this mechanism was found to be associated with loss of either α-thalassemia/mental retardation syndrome X-linked (ATRX) or death domain-associated (DAXX) protein. We previously reported that alternative...

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Identifiers

PMID: 26428317
DOI: 10.1038/modpathol.2015.114

Genes

ATRX
DAXX

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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