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Article

Integrating genomic features for prognosis in Chinese patients with diffuse large B-cell lymphoma following R-CHOP therapy.

Annals of hematology - 3 Jun 2026

Han Shi, Zhou Linghui, Zheng Haiqiong, Zhao Yi, Cai Zhen, He Jingsong, Ye Xiujin, Wu Wenjun, Sun Jie, Zheng Weiyan, Wei Guoqing, Yu Li, Wang Lixin, Gao Ke, Yue Juan, Zhang Mingming, Hu Yongxian, Huang He

Abstract excerpt

Diffuse large B-cell lymphoma (DLBCL) exhibits 30-40% rates of relapse or refractory disease after R-CHOP. Identifying patients at risk for treatment failure is essential for planning subsequent therapeutic strategies, including stem cell mobilization or cellular therapy. To identify genomic predictors in Chinese patients, we performed targeted sequencing of tumor and matched oral DNA from 147 cases. Mutations in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42234135
DOI: 10.1007/s00277-026-07085-y
PMCID: PMC13447478

Genes

MYC
SRP72
TP53
ASXL2
BCL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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