Article
B-cells in systemic sclerosis: emerging evidence from genetics to phenotypes.
Current opinion in rheumatology - 1 Nov 2015
Wu Minghua, Mohan Chandra
Abstract excerpt
PURPOSE OF REVIEW: This review aims to summarize current evidence for a role of B-cells in the pathogenesis of systemic sclerosis (SSc) from genetics to phenotypes, with an emphasis on recent insights. RECENT FINDINGS: Multiple genomic analyses have associated several B-cell signalling genes with SSc. Moreover, interesting B-cell subset alterations and activation/memory marker changes have also been documented in...
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