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Article

Diversified Control Paths: A Significant Way Disease Genes Perturb the Human Regulatory Network.

PloS one - 1 Jan 2015

Wang Bingbo, Gao Lin, Zhang Qingfang, Li Aimin, Deng Yue, Guo Xingli

Abstract excerpt

BACKGROUND: The complexity of biological systems motivates us to use the underlying networks to provide deep understanding of disease etiology and the human diseases are viewed as perturbations of dynamic properties of networks. Control theory that deals with dynamic systems has been successfully used to capture systems-level knowledge in large amount of quantitative biological interactions. But from the...

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Identifiers

PMID: 26284649
DOI: 10.1371/journal.pone.0135491
PMCID: PMC4540569

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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