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Article

Systems Genetics as a Tool to Identify Master Genetic Regulators in Complex Disease.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017

Moreno-Moral Aida, Pesce Francesco, Behmoaras Jacques, Petretto Enrico

Abstract excerpt

Systems genetics stems from systems biology and similarly employs integrative modeling approaches to describe the perturbations and phenotypic effects observed in a complex system. However, in the case of systems genetics the main source of perturbation is naturally occurring genetic variation, which can be analyzed at the systems-level to explain the observed variation in phenotypic traits. In contrast with...

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PMID: 27933533
DOI: 10.1007/978-1-4939-6427-7_16

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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