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Article

Co‐evolution of <scp>NK</scp> receptors and <scp>HLA</scp> ligands in humans is driven by reproduction

18 Aug 2015

Abstract excerpt

Allogeneic individuals co-exist during pregnancy in eutherian mammals. Maternal and fetal cells intermingle at the site of placental attachment in the uterus, where the arteries are remodeled to supply the fetus with oxygen and nutrients. This access by placental cells to the maternal supply line determines the growth and birth weight of the baby and is subject to stabilizing selection. Invading placental...

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PMID: 26284484
DOI: 10.1111/imr.12323

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