NK Cells and Trophoblasts

Abstract excerpt

In placental mammals, viviparity--the production of living young within the mother's body--evolved under the auspices of the immune system. Elements of immunity were incorporated, giving pregnancy a mildly inflammatory character. Formation of the placenta, the organ that feeds the fetus, involves a cooperation between maternal natural killer (NK) cells and fetal trophoblast cells that remodels the blood supply....

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