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Article

Effect of Ly49 haplotype variance on NK cell function and education.

Journal of immunology (Baltimore, Md. : 1950) - 15 Oct 2010

Patel Rajen, Bélanger Simon, Tai Lee-Hwa, Troke Angela D, Makrigiannis Andrew P

Abstract excerpt

The class I MHC-specific receptors expressed by murine NK cells exhibit remarkable variation. Specific activating killer Ig-related receptor/Ly49 have major effects on autoimmune and infectious disease induction and outcome in humans and mice. However, these studies are greatly affected by individual background genetics. Furthermore, the educational impact of variable inhibitory KIR/Ly49 gene numbers on NK cell...

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Share to Blotting, Southern
Share to Cell Separation
Share to Cytotoxicity, Immunologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Histocompatibility Antigens Class I

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Source

Identifiers

PMID: 20855875
DOI: 10.4049/jimmunol.1001287

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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