Obesity, Aspirin, and Risk of Colorectal Cancer in Carriers of Hereditary Colorectal Cancer: A Prospective Investigation in the CAPP2 Study.

doi:10.1200/JCO.2014.58.9952

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Article

Obesity, Aspirin, and Risk of Colorectal Cancer in Carriers of Hereditary Colorectal Cancer: A Prospective Investigation in the CAPP2 Study.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Nov 2015

Movahedi Mohammad, Bishop D Timothy, Macrae Finlay, Mecklin Jukka-Pekka, Moeslein Gabriela, Olschwang Sylviane, Eccles Diana, Evans D Gareth, Maher Eamonn R, Bertario Lucio, Bisgaard Marie-Luise, Dunlop Malcolm G, Ho Judy W C, Hodgson Shirley V, Lindblom Annika, Lubinski Jan, Morrison Patrick J, Murday Victoria, Ramesar Raj S, Side Lucy, Scott Rodney J, Thomas Huw J W, Vasen Hans F, Burn John, Mathers John C

Abstract excerpt

PURPOSE: In the general population, increased adiposity is a significant risk factor for colorectal cancer (CRC), but whether obesity has similar effects in those with hereditary CRC is uncertain. This prospective study investigated the association between body mass index and cancer risk in patients with Lynch syndrome (LS). PATIENTS AND METHODS: Participants with LS were recruited to the CAPP2 study, in which...

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PMID: 26282643
DOI: 10.1200/JCO.2014.58.9952

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MLH1
MSH2
MSH6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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