Article
Metabolic obesity phenotypes and risk of colorectal cancer in postmenopausal women.
International journal of cancer - 1 Aug 2018
Kabat Geoffrey C, Kim Mimi Y, Stefanick Marcia, Ho Gloria Y F, Lane Dorothy S, Odegaard Andrew O, Simon Michael S, Bea Jennifer W, Luo Juhua, Wassertheil-Smoller Sylvia, Rohan Thomas E
Abstract excerpt
Obesity has been postulated to increase the risk of colorectal cancer by mechanisms involving insulin resistance and the metabolic syndrome. We examined the associations of body mass index (BMI), waist circumference, the metabolic syndrome, metabolic obesity phenotypes and homeostasis model-insulin resistance (HOMA-IR-a marker of insulin resistance) with risk of colorectal cancer in over 21,000 women in the...
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