Article
A Meta-Analysis of Obesity and Risk of Colorectal Cancer in Patients with Lynch Syndrome: The Impact of Sex and Genetics.
Nutrients - 20 May 2021
Lazzeroni Matteo, Bellerba Federica, Calvello Mariarosaria, Macrae Finlay, Win Aung Ko, Jenkins Mark, Serrano Davide, Marabelli Monica, Cagnacci Sara, Tolva Gianluca, Macis Debora, Raimondi Sara, Mazzarella Luca, Chiocca Susanna, Caini Saverio, Bertario Lucio, Bonanni Bernardo, Gandini Sara
Abstract excerpt
There appears to be a sex-specific association between obesity and colorectal neoplasia in patients with Lynch Syndrome (LS). We meta-analyzed studies reporting on obesity and colorectal cancer (CRC) risk in LS patients to test whether obese subjects were at increased risk of cancer compared to those of normal weight. We explored also a possible sex-specific relationship between adiposity and CRC risk among...
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