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Article

Whole-Genome Sequencing of Growth Hormone (GH)-Secreting Pituitary Adenomas.

The Journal of clinical endocrinology and metabolism - 1 Oct 2015

Välimäki Niko, Demir Hande, Pitkänen Esa, Kaasinen Eevi, Karppinen Atte, Kivipelto Leena, Schalin-Jäntti Camilla, Aaltonen Lauri A, Karhu Auli

Abstract excerpt

CONTEXT: The somatic landscape of pituitary adenomas is largely unknown. Identification of somatic alterations aims at better understanding of tumor pathology. OBJECTIVE: The objective of the study was a genome-wide characterization of somatic single-nucleotide variants, structural variants, and copy-number aberrations in somatotropinomas. DESIGN AND SETTING: Whole-genome sequencing and single-nucleotide...

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Source

Identifiers

PMID: 26280510
DOI: 10.1210/jc.2015-3129

Genes

AIP
GNAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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