Article
Clinical Identification of Oncogenic Drivers and Copy-Number Alterations in Pituitary Tumors.
Endocrinology - 1 Jul 2017
Bi Wenya Linda, Greenwald Noah F, Ramkissoon Shakti H, Abedalthagafi Malak, Coy Shannon M, Ligon Keith L, Mei Yu, MacConaill Laura, Ducar Matt, Min Le, Santagata Sandro, Kaiser Ursula B, Beroukhim Rameen, Laws Edward R, Dunn Ian F
Abstract excerpt
Pituitary tumors are the second most common adult primary brain tumor, with a variable clinical course. Recent work has identified a number of genetic determinants of pituitary tumor subtypes, which may augment traditional histopathologic classification schemes. We sought to determine whether pituitary tumors could be stratified based on objective molecular characteristics using a clinical genomics assay. We...
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