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Epigenetic Changes in Diabetes and Cardiovascular Risk

26 May 2016

Abstract excerpt

Cardiovascular complications remain the leading causes of morbidity and premature mortality in patients with diabetes mellitus. Studies in humans and preclinical models demonstrate lasting gene expression changes in the vasculopathies initiated by previous exposure to high glucose concentrations and the associated overproduction of reactive oxygen species. The molecular signatures of chromatin architectures that...

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PMID: 27230637
DOI: 10.1161/circresaha.116.306819

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