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Article

Epigenetic basis of diabetic vasculopathy

9 Dec 2022

Abstract excerpt

Type 2 diabetes mellitus (T2DM) causes peripheral vascular disease because of which several blood-borne factors, including vital nutrients fail to reach the affected tissue. Tissue epigenome is sensitive to chronic hyperglycemia and is known to cause pathogenesis of micro- and macrovascular complications. These vascular complications of T2DM may perpetuate the onset of organ dysfunction. The burden of diabetes is...

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PMID: 36568089
DOI: 10.3389/fendo.2022.989844

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