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Article

Smooth muscle cell and arterial aging: basic and clinical aspects.

Cardiovascular research - 15 Mar 2018

Lacolley Patrick, Regnault Veronique, Avolio Alberto P

Abstract excerpt

Arterial aging engages a plethora of key signalling pathways that act in concert to induce vascular smooth muscle cell (VSMC) phenotypic changes leading to vascular degeneration and extracellular matrix degradation responsible for alterations of the mechanical properties of the vascular wall. This review highlights proof-of-concept examples of components of the extracellular matrix, VSMC receptors which connect...

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Share to Arteries
Share to Cell Plasticity
Share to Cellular Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hemodynamics

Share to Mechanotransduction, Cellular

Share to Muscle, Smooth, Vascular

Share to Myocytes, Smooth Muscle

Share to Vascular Stiffness

Source

Identifiers

PMID: 29514201
DOI: 10.1093/cvr/cvy009

Provenance

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