Article
Association in a Chinese population of a genetic variation in the early B-cell factor 1 gene with coronary artery disease.
BMC cardiovascular disorders - 10 Feb 2017
Li Yafei, Xie Zhiyong, Chen Lei, Yan Jianjun, Ma Yao, Wang Liansheng, Chen Zhong
Abstract excerpt
BACKGROUND: Early B-cell factor 1 (EBF1) is a transcription factor expressed primarily during early B cell development. Previous studies have shown EBF1 regulates blood glucose and lipid metabolism in mice with diabetes and central adiposity. Recently, a genetic variation (rs36071027) located in an EBF1 gene intron was associated with carotid artery intima-media thickness. However, whether this polymorphism is...
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