Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Production of Uniform 3D Microtumors in Hydrogel Microwell Arrays for Measurement of Viability, Morphology, and Signaling Pathway Activation

14 Aug 2015

Abstract excerpt

Despite significant investments in cancer research and drug discovery/development, the rate of new cancer drug approval is ≤5% and most cases of metastatic cancer remain incurable. Ninety-five percent of new cancer drugs fail in clinical development because of a lack of therapeutic efficacy and/or unacceptable toxicity. One of the major factors responsible for the low success rate of anticancer drug development...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3D Printing in Biomedical Research
Share to Cancer Cells and Metastasis
Share to Cellular Mechanics and Interactions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26274587
DOI: 10.1089/adt.2015.662

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Production of Uniform 3D Microtumors in Hydrogel Microwell Arrays for Measurement of Viability, Morphology, and Signaling Pathway ActivationPMID 26274587Read ↗

Non-small cell lung carcinoma spheroid models in agarose microwells for drug response studies.Semantic proximity Read ↗

Generation of uniform-sized spheroids using PDMS-based microwell devices as 3D cancer models for pharmacological profiling of drugsSemantic proximity Read ↗

Inventions and Innovations in Preclinical Platforms for Cancer ResearchSemantic proximity Read ↗

3D Droplet-Based Bioprinting of Customized <i>In Vitro</i> Head and Neck Cancer Tumor Microenvironment ModelsSemantic proximity Read ↗

Generation of Microtumors Using 3D Human Biogel Culture System and Patient-derived Glioblastoma Cells for Kinomic Profiling and Drug Response TestingSemantic proximity Read ↗

Microfluidic Platform for Drug Response Profiling in NSCLC Patient-Derived OrganoidsSemantic proximity Read ↗

Hydrogel microtumor arrays of patient melanoma recapitulate phenotypes and drug sensitivity.Semantic proximity Read ↗

Recapitulating tumor microenvironment using preclinical 3D tissueoids model for accelerating cancer research and drug screeningSemantic proximity Read ↗

A Patient-Derived Scaffold-Based 3D Culture Platform for Head and Neck Cancer: Preserving Tumor Heterogeneity for Personalized Drug TestingSemantic proximity Read ↗

High Content Screening Characterization of Head and Neck Squamous Cell Carcinoma Multicellular Tumor Spheroid Cultures Generated in 384-Well Ultra-Low Attachment Plates to Screen for Better Cancer Drug LeadsSemantic proximity Read ↗

Bioengineered Hydrogels Recapitulate Fibroblast Heterogeneity in CancerSemantic proximity Read ↗

Development of a 3D Tissue Culture–Based High-Content Screening Platform That Uses Phenotypic Profiling to Discriminate Selective Inhibitors of Receptor Tyrosine KinasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.