Article
The Interaction among Microbiota, Immunity, and Genetic and Dietary Factors Is the Condicio Sine Qua Non Celiac Disease Can Develop.
Journal of immunology research - 1 Jan 2015
Pagliari D, Urgesi R, Frosali S, Riccioni M E, Newton E E, Landolfi R, Pandolfi F, Cianci R
Abstract excerpt
Celiac disease (CD) is an immune-mediated enteropathy, triggered by dietary wheat gluten and similar proteins of barley and rye in genetically susceptible individuals. This is a complex disorder involving both environmental and immune-genetic factors. The major genetic risk factor for CD is determined by HLA-DQ genes. Dysfunction of the innate and adaptive immune systems can conceivably cause impairment of...
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