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Article

Expression of dengue virus NS3 protein in Drosophila alters its susceptibility to infection.

Fly - 1 Jan 2015

Querenet Matthieu, Danjoy Marie-Laure, Mollereau Bertrand, Davoust Nathalie

Abstract excerpt

We developed a Drosophila model in which the dengue virus NS3 protein is expressed in a tissue specific and inducible manner. Dengue virus NS3 is a multifunctional protein playing a major role during viral replication. Both protease and helicase domains of NS3 are interacting with human and insect host proteins including innate immune components of the host machinery. We characterized the NS3 transgenic flies...

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Identifiers

PMID: 26267447
DOI: 10.1080/19336934.2015.1072662
PMCID: PMC4594507

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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