Article
In vivo functional characterization of the SARS-Coronavirus 3a protein in Drosophila.
Biochemical and biophysical research communications - 18 Nov 2005
Wong S L Alan, Chen Yiwei, Chan Chak Ming, Chan C S Michael, Chan Paul K S, Chui Y L, Fung Kwok Pui, Waye Mary M Y, Tsui Stephen K W, Chan H Y Edwin
Abstract excerpt
The Severe Acute Respiratory Syndrome-Coronavirus (SARS-CoV) 3a locus encodes a 274 a.a. novel protein, and its expression has been confirmed in SARS patients. To study functional roles of 3a, we established a transgenic fly model for the SARS-CoV 3a gene. Misexpression of 3a in Drosophila caused...
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