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Pharmacogenomics of Lithium Response in Bipolar Disorder

24 Mar 2021

Abstract excerpt

Despite being the most widely studied mood stabilizer, researchers have not confirmed a mechanism for lithium’s therapeutic efficacy in Bipolar Disorder (BD). Pharmacogenomic applications may be clinically useful in the future for identifying lithium-responsive patients and facilitating personalized treatment. Six genome-wide association studies (GWAS) reviewed here present evidence of genetic variations related...

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PMID: 33804842
DOI: 10.3390/ph14040287

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