Article
P-selectin gene polymorphism associates with pulmonary hypertension in congenital heart disease.
International journal of clinical and experimental pathology - 1 Jan 2015
Li Xiao-Fei, Song Chun-Hui, Sheng Hong-Zhuan, Zhen Dong-Dong, Pan Min, Zhu Jian-Hua
Abstract excerpt
OBJECTIVE: To investigate the relationship between P-selectin gene polymorphism and congenital heart disease (CHD) with pulmonary hypertension (PAH). METHODS: 58 CHD patients with PAH (PAH-CHD), 43 CHD patients without PAH and 205 healthy subjects were included in this study. The concentration of plasma P-selectin was determined by ELISA kits; the direct sequencing of PCR products was used to analyze the...
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