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Article

Glutathione S-transferase P1 gene rs4147581 polymorphism predicts overall survival of patients with hepatocellular carcinoma: evidence from an enlarged study.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 2016

Wang Zhixin, Qu Kai, Niu Wenquan, Lin Ting, Xu Xinsen, Huang Zichao, Liu Sushun, Liu Sinan, Chang Hulin, Liu Yamin, Dong Xiaoqun, Liu Chang, Zhang Yuelang

Abstract excerpt

As the most important detoxifying enzymes in liver, glutathione S-transferases (GSTs) can protect hepatocytes against carcinogens. We conducted a large cohort study to investigate the prognostic value of single nucleotide polymorphisms (SNPs) in seven encoding genes of GSTs for hepatocellular carcinoma (HCC). Twelve SNPs were genotyped and correlated with overall survival in 469 HCC patients. The median follow-up...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26260272
DOI: 10.1007/s13277-015-3871-7

Genes

GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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