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Article

Analysis of image-based phenotypic parameters for high throughput gene perturbation assays.

Computational biology and chemistry - 1 Oct 2015

Song Mee, Jeong Euna, Lee Tae-Kyu, Tsoy Yury, Kwon Yong-Jun, Yoon Sukjoon

Abstract excerpt

Although image-based phenotypic assays are considered a powerful tool for siRNA library screening, the reproducibility and biological implications of various image-based assays are not well-characterized in a systematic manner. Here, we compared the resolution of high throughput assays of image-based cell count and typical cell viability measures for cancer samples. It was found that the optimal plating density...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26256799
DOI: 10.1016/j.compbiolchem.2015.07.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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