Article
IL10 Promoter Polymorphisms are Associated with Rheumatic Heart Disease in Saudi Arabian Patients.
Pediatric cardiology - 1 Jan 2016
Abdallah Atiyeh M, Alnuzha Aisha, Al-Mazroea Abdulhadi H, Eldardear Amr E, AlSamman Ala Y, Almohammadi Yousef, Al-Harbi Khalid M
Abstract excerpt
Rheumatic heart disease (RHD) is an inflammatory disease that develops following streptococcal infections. IL10 helps to balance immune responses to pathogens. IL10 polymorphisms have been associated with RHD, although results remain inconclusive. Our aim was to investigate the association between IL10 polymorphisms and RHD in Saudi Arabian patients. IL10 promoter polymorphisms (-1082A/G, -829C/T, and -592C/A)...
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