Article
TP53 and FGFR3 Gene Mutation Assessment in Urine: Pilot Study for Bladder Cancer Diagnosis.
Anticancer research - 1 Sept 2015
Noel Nicolas, Couteau Jerome, Maillet Geraldine, Gobet Françoise, D'Aloisio Françoise, Minier Christophe, Pfister Christian
Abstract excerpt
AIM: To assess, in a prospective clinical research study, a new non-invasive and reliable test to accurately detect tumor protein 53 (TP53) and fibroblast growth factor receptor-3 (FGFR3) mutations in cells in urine. MATERIALS AND METHODS: TP53 mutations were analyzed using the functional analysis of separated allele in yeast (FASAY) method, which allows functional analysis of the P53 protein, and FGFR3 mutations...
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