Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Microsatellite Instability and Colorectal Cancer

1 Oct 2011

Abstract excerpt

CONTEXT: About 15% of colorectal cancers are characterized by genomic microsatellite instability, and of these, about 1 in 5 (2%-4% overall) are due to Lynch syndrome, a dominantly inherited condition predisposing the patient to cancers of multiple organ systems, including the gastrointestinal tract. Identification of individuals with Lynch syndrome allows for increased surveillance of the affected individual and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood disorders and treatments
Share to Colorectal Cancer Screening and Detection
Share to Genetic factors in colorectal cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21970482
DOI: 10.5858/arpa.2011-0035-ra

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Microsatellite Instability and Colorectal CancerPMID 21970482Read ↗

Era of universal testing of microsatellite instability in colorectal cancerSemantic proximity Read ↗

Targeted Cancer Next-Generation Sequencing as a Primary Screening Tool for Microsatellite Instability and Lynch Syndrome in Upper Gastrointestinal Tract CancersSemantic proximity Read ↗

Molecular Diagnostics of Colorectal CancerSemantic proximity Read ↗

Lynch syndrome and colorectal cancer: A review of current perspectives in molecular genetics and clinical strategiesSemantic proximity Read ↗

Lynch syndrome in the 21st century: clinical perspectives.Semantic proximity Read ↗

Lynch Syndrome: An Updated ReviewSemantic proximity Read ↗

Systematic immunohistochemical screening for Lynch syndrome in colorectal cancer: a single centre experience of 486 patients.Semantic proximity Read ↗

Revised Bethesda Guidelines for Hereditary Nonpolyposis Colorectal Cancer (Lynch Syndrome) and Microsatellite InstabilitySemantic proximity Read ↗

Molecular genetics of microsatellite-unstable colorectal cancer for pathologistsSemantic proximity Read ↗

Microsatellite instability in colorectal cancer.Semantic proximity Read ↗

Clinical Uses of Microsatellite Instability Testing in Colorectal Cancer: An Ongoing ChallengeSemantic proximity Read ↗

Lynch-like Syndrome: Potential Mechanisms and ManagementSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.