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Article

Dissecting the function of Atg1 complex in Dictyostelium autophagy reveals a connection with the pentose phosphate pathway enzyme transketolase.

Open biology - 1 Aug 2015

Mesquita Ana, Tábara Luis C, Martinez-Costa Oscar, Santos-Rodrigo Natalia, Vincent Olivier, Escalante Ricardo

Abstract excerpt

The network of protein-protein interactions of the Dictyostelium discoideum autophagy pathway was investigated by yeast two-hybrid screening of the conserved autophagic proteins Atg1 and Atg8. These analyses confirmed expected interactions described in other organisms and also identified novel interactors that highlight the complexity of autophagy regulation. The Atg1 kinase complex, an essential regulator of...

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Identifiers

PMID: 26246495
DOI: 10.1098/rsob.150088
PMCID: PMC4554924

Genes

TKT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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