Article
Function of the Dictyostelium discoideum Atg1 kinase during autophagy and development.
Eukaryotic cell - 1 Oct 2006
Tekinay Turgay, Wu Mary Y, Otto Grant P, Anderson O Roger, Kessin Richard H
Abstract excerpt
When starved, the amoebae of Dictyostelium discoideum initiate a developmental process that results in the formation of fruiting bodies in which stalks support balls of spores. The nutrients and energy necessary for development are provided by autophagy. Atg1 is a protein kinase that regulates the induction of autophagy in the budding yeast Saccharomyces cerevisiae. In addition to a conserved kinase domain,...
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