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Article

Genetic determinants of FOXM1 overexpression in epithelial ovarian cancer and functional contribution to cell cycle progression.

Oncotarget - 29 Sept 2015

Barger Carter J, Zhang Wa, Hillman Joanna, Stablewski Aimee B, Higgins Michael J, Vanderhyden Barbara C, Odunsi Kunle, Karpf Adam R

Abstract excerpt

The FOXM1 transcription factor network is frequently activated in high-grade serous ovarian cancer (HGSOC), the most common and lethal subtype of epithelial ovarian cancer (EOC). We used primary human EOC tissues, HGSOC cell lines, mouse and human ovarian surface epithelial (OSE) cells, and a murine transgenic ovarian cancer model to investigate genetic determinants of FOXM1 overexpression in EOC, and to begin to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Ovarian Epithelial

Share to Cystadenocarcinoma, Serous

Share to E2F1 Transcription Factor

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Source

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Identifiers

PMID: 26243836
DOI: 10.18632/oncotarget.4546
PMCID: PMC4695012

Genes

FOXM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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