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Article

Enhanced ZNF521 expression induces an aggressive phenotype in human ovarian carcinoma cell lines.

PloS one - 1 Jan 2022

Scicchitano Stefania, Montalcini Ylenia, Lucchino Valeria, Melocchi Valentina, Gigantino Valerio, Chiarella Emanuela, Bianchi Fabrizio, Weisz Alessandro, Mesuraca Maria

Abstract excerpt

Epithelial ovarian carcinoma (EOC) is the most lethal gynecological tumor, that almost inevitably relapses and develops chemo-resistance. A better understanding of molecular events underlying the biological behavior of this tumor, as well as identification of new biomarkers and therapeutic targets are the prerequisite to improve its clinical management. ZNF521 gene amplifications are present in >6% of OCs and its...

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Source

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Identifiers

PMID: 36191006
DOI: 10.1371/journal.pone.0274785
PMCID: PMC9529122

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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